Which medication is used to prevent hemorrhagic cystitis?

The medication used to prevent hemorrhagic cystitis is Mesna. Mesna acts as a protective agent against the toxic effects of certain chemotherapy drugs, particularly ifosfamide and cyclophosphamide, which can cause damage to the bladder mucosa. By binding to the metabolites of these drugs, Mesna helps to neutralize their harmful effects, thereby reducing the risk of bleeding and inflammation in the bladder, which are characteristic features of hemorrhagic cystitis.

Mesna is specifically indicated for this purpose and is typically administered either before or alongside the chemotherapy agents to maximize its protective effects. Its use is an important aspect of supportive care in oncology, helping to minimize complications associated with certain chemotherapeutic regimens.